제품소개

PRODUCT

Dialysis Systems

SpectraFlo™ Dynamic Dialysis Systems are the only commercially available systems for scalable dynamic dialysis from lab scale to large volume processing.

  • CONTINUOUS BUFFER FLOW : No manual buffer changes Walkaway convenience
  • INTEGRATED : Includes dialysis tank, pump, reservoirs, membrane Fast implementation time
  • SCALABLE : Scale up from lab to process scale Scale out from 1 to 6 tanks in series
  • INCREASED PURIFICATION EFFICIENCY : Sealed self-enclosed design Minimized exposure to external contaminants
  • INNOVATIVE MOBILE SYSTEM : Large-scale, small footprint Series operation conserves buffer

SpectraFlo™ Lab
and Process Systems

  • 1Dialysis tank
  • 2KR1 peristaltic pump
  • 3Dialysis reservoir
  • 4Dialysis membrane
  • 10~200㎖
  • 150㎖~2L

SpectraFlo™ Mobile Dialysis Systems

  • 1Cart
  • 2Dialysis tanks
  • 3KR1 peristaltic pump
  • 4Dialysis reservoir
  • 5Wet-work tray (mounted)
  • 6Pump shelf (mounted)
6~12L

DYNAMIC DIALYSIS APPLICATIONS

Dynamic dialysis is ideal for the purification of viscous fluids and hydrogels (hyaluronic acid – HA) that cannot be filtered.
Where traditional filtration methods may fail, dynamic dialysis uses flow dynamics to increase both the rate and efficiency of dialysis.

APLICATIOMS WHY DYNAMIC DIALYSIS IS PREFERRED EXAMPLE
Delicate Sample Gentle separation without shear stress Labile proteins and intact viruses
Viscous samples (Hyaluronic Acid) Process hydrogels that are too viscous for filtration Cross-linked Hyaluronic Acid for aesthetics and orthobiologics
Protein refolding Refold proteins to native state using gradual pH change through buffer flow Overexpressed proteins containing inclusion bodies
High debris lysate Will not foul like pressure driven filtration Demineralized bone matrix for othopedic surgery
Polymer and Biopolymer synthesis Low MWCO enables removal of unbound low molecular weight monomer Oligonucleotides and polypeptides
Scale up of any static dialysis application Easy scale up without complex validation or financial burden of filtration Desalting

TANK SIZES

SpectraFlo™ MODES OF OPERATION

Case Study: Model of Dynamic Dialysis

This model of a GMP batch production of shear-sensitive protein shows an efficent scale-up of large volume dynamic dialysis for purification.

*Batch-customized:pre-cut 115cm, irradiated, GMP batch qty & packaging

Case Study: Model of Dynamic Dialysis

FEATURES BENEFITS
Up to 6 tanks in series Scale up to 12L Sample Size
Parallel or series operation Optimize buffer usage
Wet work tray Prepare and load samples with secondary containment
Drain manifold Load and drain buffer easily
BSE/TSE free polypropylene construction Use for GMP processes and cleanroom manufacturing
Collapsible shelves and tubing hooks Store complete system in compact space